Effect of Infection with Scabies on The Adrenaline Hormone of Patients with Chronic Diseases in Basra City/ Southern Iraq

Abstract

Scabies, a parasitic skin infestation by the burrowing “itch” mite Sarcoptes scabiei, causes significant health problems for children and adults worldwide. Crusted scabies is a particularly severe form of scabies in which mites multiply into the millions, causing extensive skin crusting. The symptoms and signs of scabies suggest host immunity to the scabies mite. The defense against stress is executed by the hypothalamic-pituitary-adrenal axis and the sympathetic-adrenal medullary system. Adrenal gland is a major effector organ of stress system. During stress, adrenal gland rapidly responds with increased secretion of glucocorticoids (GCs) and catecholamines into circulation, which hormones, in turn, affect metabolism, to provide acute energy, vasculature to increase blood pressure, and the immune system to prevent it from extensive activation. . The current study examined (80) people, of whom (16) had negative control samples and (64) had scabies and had chronic diseases such as heart disease, diabetes, pressure, lung, liver, kidneys, ulcers, cancer, anemia and epilepsy, the current study recorded the highest levels of adrenaline using the associated immunosorbent assay technique With the enzyme (ELISA), which is (523 pg / ml) for patients suffering from chronic heart disease and infected with the scabies mite parasite and their number (14) out of (64) have other chronic diseases and their percentage was (21.88%) and the current study recorded the lowest levels of the hormone adrenaline. In patients with scabies and suffering from epilepsy at a rate (219 pg / ml) percentage  (1.56%), which shows the hormone levels in patients with scabies and suffering from chronic diseases and comparing them with the control samples.